| 产品详情 |
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| Product Name | AZ 628 |
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| Description | A quinazilinone that inhibits several Raf kinases, including B-Raf, B-RafV600E, and c-Raf-1 (IC50s = 105, 34, and 29 nM in vitro); inhibits anchorage-dependent and -independent growth, induces cell cycle arrest, and causes apoptosis in colon and melanoma cell lines carrying B-RafV600E mutations |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1007871-?84-?2 Raf kinase inhibitor mutation B-Raf BRAFV600E c-Raf-1 cancer inhibit inhibition cellular cell pathway melanoma AZ628 AZ-628 quinazilinone b c Raf c-Raf-1 tyrosine VEGFR2 DDR2 Lyn Flt1 FMS colon mutation anchorage cycle arrest apoptosis |
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| Gene, Accession, CAS # | CAS: 878739-06-1 |
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| Catalog # | 15336-5 |
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| Price | |
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| Order / More Info | AZ 628 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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