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| Product Name | Recombinant Human Ganglioside GM2 activator (GM2A) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 44.6kDa. Full Length of Mature Protein: 32-193aa. N-terminal GST-tagged. Homo sapiens (Human). The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity. Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from mbranes and presents th in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Cerebroside sulfate activator protein; GM2-APSphingolipid activator protein 3; SAP-3 |
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| Gene, Accession, CAS # | GM2A, UniProt: P17900 |
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| Catalog # | RPC25846 |
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| Order / More Info | Recombinant Human Ganglioside GM2 activator (GM2A) from BIOMATIK |
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| Product Specific References | n/a |
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