| 产品详情 |
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| Product Name | Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) protein (Biotin) |
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| Description | Cytochrome P450 2D6 is a member of a complex family of microsomal enzymes (mono-oxygenases) present in the endoplasmic reticulum membrane, which perform detoxification reaction on xenobiotic compounds. Cytochrome P450 2D6 is the molecular target of autoantibodies against the liver kidney microsomal antigen 1 (LKM 1) which has been classically defined by immunofluorescence microscopy. The presence of these autoantibodies is considered indicative of Autoimmune Hepatitis Type 2, LKM 1 antibodies have also been detected in patients with hepatitis C viral infection. The International Autoimmune Hepatitis Group therefore has subdivided the AIH type 2 into two subgroups: 2a with HCV and 2b without HCV. AIH 2a patients are often over 40 and predominantly male.The use of a purified recombinant Cytochrome P450 2D6 antigen allows the differentiation of autoimmune hepatitis from drug-induced hepatitis where transient autoantibodies to other P450 family members occur which cannot be differentiated by immunofluorescence techniques Synonyms: Cytochrome P450 2D6, CYPIID6, P450-DB1, Debrisoquine 4-hydroxylase, CYP2D6, CPD6, CYP2D, CYP2D@, CYP2DL1, P450C2D, MGC120389, MGC120390, LKM1, liver/kidney microsomal antigen 1 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | Transfected Cell Culture (TCC),Western Blotting (WB) |
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| Other Names | CYP2D42|MGC64445|cyp2d2|cyp2d6-a|Cyp2d18|Cyp2d22|Cyp2d4v1|Cyp2d4v2|Cyp2d6|CPD6|CYP2D|CYP2D7AP|CYP2D7BP|CYP2D7P2|CYP2D8P2|CYP2DL1|CYPIID6|P450-DB1|P450C2D|P450DB1|CYP2D6 |
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| Gene, Accession, CAS # | Gene ID: 1565 |
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| Catalog # | ABIN805485 |
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| Order / More Info | Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) protein (Biotin) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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