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| Product Name | Recombinant Human Ryanodine receptor 1 (RYR1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 63.3kDa. Partial: 1-534aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal bryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during bryogenesis. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Skeletal muscle calcium release channelSkeletal muscle ryanodine receptorSkeletal muscle-type ryanodine receptorType 1 ryanodine receptor |
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| Gene, Accession, CAS # | RYR1, UniProt: P21817 |
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| Catalog # | RPC21957 |
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| Price | |
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| Order / More Info | Recombinant Human Ryanodine receptor 1 (RYR1), partial from BIOMATIK |
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| Product Specific References | n/a |
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