| 产品详情 |
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| Product Name | BAPTA AM |
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| Description | Purity >98%. BAPTA is membrane-impermeable calcium chelator that binds extracellular calcium ions (Kd = 0.11 µM), with selectivity over magnesium ions or protons. BAPTA and its derivatives can also be used as calcium indicators, since the absorption maximum for BAPTA changes when it is complexed with calcium (absorption maxima free/complexed = 254/274 nm, emission maxima free/complexed = 363/363 nm). BAPTA AM is a cell permeable analog of BAPTA that binds calcium only after the acetoxymethyl group is removed by cytoplasmic esterases. It is commonly used at 10-100 µM to evaluate the role of intracellular calcium in cell signaling. It can also be used in animals. BAPTA AM also inhibits voltage-gated potassium (Kv ) channels, including Kv 1.3, Kv 1.5, and Kv 11.1 (Ki = 1.45, 1.23, and 1.30 µM, respectively). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis [N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-1,1'-bis [(acetyloxy)methyl] ester-glycine, BAPTA Acetoxymethyl ester |
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| Gene, Accession, CAS # | CAS: 126150-97-8 |
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| Catalog # | LS-H6736 |
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| Price | |
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| Order / More Info | BAPTA AM from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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