产品详情 |
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Product Name | Ponatinib (AP24534) |
Description | MW: 532.56. |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | MBS8506540 |
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Order / More Info | Ponatinib (AP24534) from MYBIOSOURCE INC. |
Product Specific References | AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia,Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance Thomas O'Hare, William C. Shakespeare,et al. Cancer Cell 2009 November 6;16(5): 401 -412 Discoveryof3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N- 4-[(4-methylpiperazin-1-yl)-methyl]-3-(trifluoromethyl)phenyl benzamide (AP24534), a Potent, Orally Active Pan-Inhibitor of Breakpoint Cluster Region-Abelson (BCR-ABL) Kinase Including the T315I Gatekeeper M |
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