产品详情 |
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Antigenic Specificity | Cytokeratin 17 |
Clone | E3 |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG2b, kappa |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:40-1:80 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytokeratin 17 Monoclonal Antibody (E3). The type I keratin 17 (K17) shows a peculiar localization in human epithelial appendages including hair follicles, which undergo a growth cycle throughout adult life. Additionally K17 is induced, along with K6 and K16, early after acute injury to human skin. Predominant expression of K17 and the frequent expression of K8 and K19, with little K6/K16 and K1/K10 expression are the characteristic features of basal cell carcinomas (BCC), suggesting that BCC is differentiated towards undifferentiated follicular epithelia, most probably hair bulge cells. |
Immunogen | n/a |
Other Names | 39.1, CK-17, cytokeratin-17, keratin, type I cytoskeletal 17, keratin-17 |
Gene, Accession # | Entrez: 287702, 3872; Uniprot: Q04695, Q6IFU8 |
Catalog # | MA5-13539 |
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Order / More Info | Cytokeratin 17 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 15096140, 16857790, 18383851, 19003862, 19156550, 23292936, 23765132, 26026368 |
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