产品详情 |
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Antigenic Specificity | Cytokeratin 17 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:200, Western Blot: 1:25 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytokeratin 17 Polyclonal Antibody. Keratin 17 plays a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. It may be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial stem cells. It also acts as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. It is required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state and modulates the function of TNF-alpha in the specific context of hair cycling. It regulates protein synthesis and epitheli |
Immunogen | n/a |
Other Names | K17, PC, PC2, PCHC1, 39.1, CK-17, cytokeratin-17, keratin 17 epitope S1, keratin 17 epitope S2, keratin 17 epitope S4, keratin, type I cytoskeletal 17, keratin-17 |
Gene, Accession # | Entrez: 3872; Uniprot: Q04695 |
Catalog # | PA5-32461 |
Price | |
Order / More Info | Cytokeratin 17 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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