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| Product Name | Recombinant Human Gamma-secretase subunit APH-1A (APH1a), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 42.9kDa. Partial: 1-247aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Aph-1alpha; Presenilin-stabilization factor |
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| Gene, Accession, CAS # | APH1a, UniProt: Q96BI3 |
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| Catalog # | RPC20824 |
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| Order / More Info | Recombinant Human Gamma-secretase subunit APH-1A (APH1a), partial from BIOMATIK |
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| Product Specific References | n/a |
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