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| Product Name | Recombinant Human Myeloid leukemia factor 1 (MLF1) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 57.6kDa. Full Length: 1-268aa. N-terminal GST-tagged. Homo sapiens (Human). Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Myelodysplasia-myeloid leukemia factor 1 |
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| Gene, Accession, CAS # | MLF1, UniProt: P58340 |
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| Catalog # | RPC21670 |
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| Order / More Info | Recombinant Human Myeloid leukemia factor 1 (MLF1) from BIOMATIK |
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| Product Specific References | n/a |
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