| 产品详情 |
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| Product Name | NSC 185058 |
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| Description | An inhibitor of ATG4B; inhibits ATG4B cleavage of LC3B-GST (IC50 = 51 µM) and reduces LC3B lipidation induced by starvation in Saos-2 cells; reduces starvation-induced autophagy and prevents autophagic vacuole formation in Saos-2 and MDA-MB-468 cells (100 µM); decreases autophagy in vivo in mouse liver, inhibits tumor growth in mouse xenograft model, and decreases the number of autophagic vacuoles in osteosarcoma tumors (100 mg/kg) |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | NSC185058 ATG-4B LC-3B LC38GST Saos2 MDAMB468 RPS-6 |
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| Gene, Accession, CAS # | CAS: 39122-38-8 |
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| Catalog # | 23957-1 |
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| Price | |
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| Order / More Info | NSC 185058 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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