| 产品详情 |
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| Product Name | CK2 Inhibitor 10 |
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| Description | Purity >98% by HPLC, MS, NMR. Potent and ATP-competitive inhibitor of casein kinase 2 (IC50 CK2alpha=32nM and IC50 CK2alpha'=46nM). Potently also inhibits DYRK1B and FLT3. Anticancer compound. Exhibits potent cytotoxicity towards lung cancer cells A549, colorectal cancer cells HCT-116 and breast cancer cells MCF-7. Promoted cAMP-induced thermogenesis in white adipocytes. CK2 inhibition ameliorates diet-induced obesity and insulin resistance in mice in vivo by promoting UCP1-dependent thermogenesis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CK2-VIII, 4-(2-(4-Methoxybenzamido)thiazol-5-yl)benzoic acid |
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| Gene, Accession, CAS # | CAS: 1361229-76-6 |
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| Catalog # | LS-H245 |
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| Order / More Info | CK2 Inhibitor 10 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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