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Product Name | C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) protein |
Description | VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Alternative Names: FIGF protein, Vascular Endothelial Growth Factor-D protein |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | FIGF|vegfd|vegf-d|VEGFD|AI325264|VEGF-D|Vegfd|Vegf-d |
Gene, Accession, CAS # | Gene ID: 2277 |
Catalog # | ABIN935904 |
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Order / More Info | C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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