| 产品详情 |
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| Product Name | Phomopsin A |
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| Description | Purity >98%. Phomopsins are a family of mycotoxins produced by the fungus D. toxica, which predominantly infects lupines. Ingestion of lupines infected with D. toxica causes lupinosis, a degenerative disorder that can result in acute liver damage, brain damage, and death. Phomopsin A is a cyclic hexapeptide mycotoxin that binds Beta-tubulin in a vinca domain, overlapping with the site targeted by vinblastine and other tubulin inhibitors. It binds Beta-tubulin from higher organisms but not Alpha-tubulin or fungal mycelial tubulin. Phomopsin A blocks microtubule growth, modulates the dynamics of microtubules, and interferes with mitosis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2E)-(BetaS)-3-chloro-Beta,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-(2E)-2,3-didehydroisoleucyl-2,3-didehydro-aspartic acid, cyclic (15 ?3)-ether, NSC 381839 |
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| Gene, Accession, CAS # | CAS: 64925-80-0 |
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| Catalog # | LS-H9383 |
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| Order / More Info | Phomopsin A from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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