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| Product Name | Philanthotoxin 74 (hydrochloride) |
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| Description | Purity >97%. Philanthotoxin 74 (PhTx-74) is a synthetic analog of the naturally-occurring wasp venom toxin philanthotoxin-4,3,3. It is a subtype-selective AMPA receptor antagonist that inhibits homomeric GluR1 and GluR3 as well as heteromeric GluR1/2 receptors (80-100% of glutamate-evoked currents inhibited at 100 µM). It exhibits minimal to no effect on monomeric GluR2 or heteromeric GluR2/3 receptors at concentrations up to 500 µM. PhTx-74 inhibits the GluR5(Q) receptor with a Ki value of 0.29 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[7-[(4-aminobutyl)amino]heptyl]-4-hydroxy-aS-[(1-oxobutyl)amino]-benzenepropanamide, dihydrochloride, PhTx-74 |
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| Gene, Accession, CAS # | CAS: 1227301-51-0 |
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| Catalog # | LS-H101 |
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| Price | |
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| Order / More Info | Philanthotoxin 74 (hydrochloride) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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