| 产品详情 |
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| Antigenic Specificity | NMDAR2B Tyr1252 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 680 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NMDAR2B (Tyr1252) Polyclonal Antibody, Alexa Fluor® 680 Conjugated. • Target Background: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity). |
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| Immunogen | KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1252. Immunogen Range: 1230-1280/1484 |
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| Other Names | Phosphorylated, phospho-MRD6; NR2B; hNR3; GluN2B; NMDAR2B; Glutamate receptor ionotropic, NMDA 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NR3; GRIN2B |
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| Gene, Accession # | Gene ID: 2904, SwissProt: Q13224 |
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| Catalog # | bs-5380R-A680 |
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| Price | |
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| Order / More Info | NMDAR2B Tyr1252 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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