产品详情 |
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Antigenic Specificity | Phospho-SMC1 (Ser957) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunoprecipitation: 2-6 µg/mg lysate, Western Blot: 1:200-1:2,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-SMC1 (Ser957) Polyclonal Antibody. Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndro |
Immunogen | n/a |
Other Names | RP6-29D12.1, CDLS2, DKFZp686L19178, DXS423E, KIAA0178, MGC138332, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB |
Gene, Accession # | Entrez: 8243; Uniprot: Q14683 |
Catalog # | A300-045A |
Price | |
Order / More Info | Phospho-SMC1 (Ser957) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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