产品详情 |
Edit |   |
Antigenic Specificity | Phospho-SMC1 (Ser957) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phospho-SMC1 (Ser957) Polyclonal Antibody. Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repai |
Immunogen | n/a |
Other Names | Chromosome segregation protein SmcB, DXS423E, KIAA0178, SB1.8/DXS423E protein, SM1A, SMC1A, SMC1L1, SMC1alpha protein, Sb1.8, Structural maintenance of chromosome 1-like 1 protein |
Gene, Accession # | Entrez: 24061, 8243; Uniprot: Q14683, Q9CU62 |
Catalog # | PA5-39699 |
Price | |
Order / More Info | Phospho-SMC1 (Ser957) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
产品资料 |
|
|