产品详情 |
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Antigenic Specificity | NBS1 |
Clone | oligoclonal |
Host Species | Recombinant Rabbit |
Reactive Species | human, mouse |
Isotype | IgG |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NBS1 Antibody, ABfinity™ Rabbit Oligoclonal. Nibrin (NBS1) is a member of the double-strand break repair complex MRE11/RAD50/NBN (MRN) which is involved in DNA double-strand break repair, DNA damage-induced checkpoint activation and plays a critical role in the maintenance of chromosome integrity. Nibrin contains two modules found in cell cycle checkpoint proteins, a forkhead-associated domain adjacent to a breast cancer carboxy-terminal domain. Mutations in this gene are associated with Nijmegen breakage syndrome and maybe the cause of cancer predisposition and aplastic anemia. |
Immunogen | n/a |
Other Names | NBS, NBS1, P95 |
Gene, Accession # | Entrez: 27354, 4683; Uniprot: O60934, Q9R207 |
Catalog # | 711701 |
Price | |
Order / More Info | NBS1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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