产品详情 |
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Antigenic Specificity | NBS1 |
Clone | 1D7 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunoprecipitation: Assay dependent, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NBS1 Monoclonal Antibody (1D7). Nijmegen breakage syndrome (NBS, nibrin) is an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The 1C3 antibody recognizes the 95 kDa NBS protein which contains a fork FHA head-associated domain that is adjacent to BRCT, a breast cancer C terminal domain, that has been implicated in protein-protein interactions. NBS is member of the Mre11/Rad50, p400 double-strand break repair complex involved in double-strand break repair and cell-cycle checkpoint functions. |
Immunogen | n/a |
Other Names | AT-V1, AT-V2, ATV, FLJ10155, MGC87362, NBS, NBS1, P95 |
Gene, Accession # | Entrez: 27354, 4683, 85482; Uniprot: O60934, Q9JIL9, Q9R207 |
Catalog # | MA1-23265 |
Price | |
Order / More Info | NBS1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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