产品详情 |
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Antigenic Specificity | Apolipoprotein A5 |
Clone | 1G5G9 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | ELISA: 1:100-1:2000, Immunocytochemistry: 1:250, Immunofluorescence: 1:250, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apolipoprotein A5 Monoclonal Antibody (1G5G9). Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-4 (PPAR-alpha) agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipo |
Immunogen | n/a |
Other Names | ApoA5 |
Gene, Accession # | Entrez: 116519; Uniprot: Q6Q788 |
Catalog # | MA1-16809 |
Price | |
Order / More Info | Apolipoprotein A5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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