产品详情 |
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Antigenic Specificity | ZIPK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ZIPK Polyclonal Antibody. Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase. ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family. ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase), which is a mediator of apoptosis induced by -gamma interferon. Overexpression of ZIP kinase induces apoptosis. ZIP and DAP kinases represent a novel kinase family, which mediates apoptosis t |
Immunogen | n/a |
Other Names | ZIP, ZIPK; DAP kinase 3; DAP-like kinase; ZIP kinase isoform; ZIP-kinase; dlk; zipper-interacting protein kinase |
Gene, Accession # | Entrez: 13144, 1613, 64391; Uniprot: O43293, O54784, O88764 |
Catalog # | PA5-19902 |
Price | |
Order / More Info | ZIPK Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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