产品详情 |
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Antigenic Specificity | IRF3 Ser396 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, IHC-P, IF(IHC-P), IF(ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IRF3 (Ser396) Polyclonal Antibody. • Target Background: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and lat |
Immunogen | KLH conjugated synthetic phosphopeptide derived from human IRF3 around the phosphorylation site of Ser396. Immunogen Range: 375-425/427 |
Other Names | Phosphorylated, phospho-Interferon regulatory factor 3; IRF-3; IRF3 |
Gene, Accession # | Gene ID: 3661, SwissProt: Q14653 |
Catalog # | bs-3195R |
Price | |
Order / More Info | IRF3 Ser396 Antibody from BIOSS ANTIBODIES |
Product Specific References | Le Bel, Manon, et al. (2015) PLoS ONE 10.10:e0139856. PubMed: 26444420 // Ando, Makoto, et al. (2017) Free Radic Biol Med. PubMed: 28870522 // Egarnes, Benoit, et al. (2017) PLOS ONE. // Menasria et al. (2013) J.Virol. 87:7301-8. PubMed: 23596298 // Egarnes et al. (2017) PLoS.One. 12:e0186639. PubMed: 29053748 |
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