| 产品详情 |
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| Antigenic Specificity | IRF7 Ser471 + Ser472 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IRF7 (Ser471 + Ser472) Antibody. • Target Background: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88 |
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| Immunogen | KLH conjugated synthetic phosphopeptide derived from human IRF7 around the phosphorylation site of Ser471/472. Immunogen Range: 450-490/503 |
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| Other Names | Phosphorylated, phospho-IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H; Interferon regulatory factor 7; IRF-7; IRF7 |
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| Gene, Accession # | Gene ID: 3665, SwissProt: Q92985 |
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| Catalog # | bs-3196R |
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| Price | |
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| Order / More Info | IRF7 Ser471 + Ser472 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Han, Young Woo, et al. (2014) PLoS Pathog 10.9:e103882. PubMed: 25188232 // Le Bel, Manon, et al. (2015) PLoS ONE 10.10:e0139856. PubMed: 26444420 // Egarnes, Benoit, et al. (2017) PLOS ONE. // Menasria et al. (2013) J.Virol. 87:7301-8. PubMed: 23596298 // Egarnes et al. (2017) PLoS.One. 12:e0186639. PubMed: 29053748 |
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