| 产品详情 |
| Edit |   |
|---|
| Product Name | UMI-77 |
|---|
| Description | Purity >98% by HPLC. UMI-77 is a novel, selective, Mcl-1 SMI inhibitor. UMI-77 is selective for Mcl-1 over other members of the antiapoptotic Bcl-2 family with a Ki of 490 nM. UMI-77 acts by binding to the BH3-binding groove of Mcl-1, blocking the heterodimerization of Mcl-1/Bax and Mcl-1/Bak. It inhibits cell growth and induces apoptosis in pancreatic cancer cells. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | 2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynaphthalen-2-yl]sulfanylacetic acid |
|---|
| Gene, Accession, CAS # | CAS: 518303-20-3 |
|---|
| Catalog # | LS-H3819 |
|---|
| Price | |
|---|
| Order / More Info | UMI-77 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|