产品详情 |
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Antigenic Specificity | RTCA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RTCA Polyclonal Antibody. RTCD1 catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) the enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A; (C) a non catalytic nucleophilic attack by the adjacent 2'hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. There are two named isoforms. |
Immunogen | n/a |
Other Names | RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase, RNA terminal phosphate cyclase domain-containing protein 1, RTC domain-containing protein 1, RTCA, RPC, RPC1, RTC1 |
Gene, Accession # | Entrez: 8634; Uniprot: O00442 |
Catalog # | PA5-39429 |
Price | |
Order / More Info | RTCA Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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