| 产品详情 |
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| Product Name | GSK-J2 (sodium salt) |
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| Description | Purity >90%. The histone H3 lysine 27 (H3K27) demethylase JMJD3 plays important roles in the transcriptional regulation of cell differentiation, development, the inflammatory response, and cancer. GSK-J2 is a pyridine regio-isomer of GSK-J1 which poorly inhibits JMJD3 (IC50 > 100 µM), making it an appropriate negative control for in vitro studies involving GSK-J1. For in vivo research, cell-permeable prodrug forms of GSK-J1 and GSK-J2 are available as GSK-J4 and GSK-J5 , respectively. See the Structural Genomics Consortium (SGC) website for more information. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-3-yl)pyrimidin-4-yl)amino)propanoic acid, monosodium salt |
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| Gene, Accession, CAS # | CAS: 2108665-15-0 |
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| Catalog # | LS-H8030 |
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| Price | |
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| Order / More Info | GSK-J2 (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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