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Product Name | PGD, 1-483aa, Human, His tag, E Coli |
Description | MW: 55.3 kDa (503aa). Purity >95% by SDS-PAGE. PGD (Phosphogluconate dehydrogenas), also known as 6PGD, is a 483 amino acid enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in a |
Size | 0.1 mg, 0.5 mg |
Concentration | 1 mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | [Phosphogluconate dehydrogenase; 6PGD; Phosphogluconate dehydrogenase 0610042A05Rik; Au019875; C78335; 6 phosphogluconate dehydrogenase; decarboxylating; OTTMuSP00000011754; RP23-249G3.4,] |
Gene, Accession, CAS # | PGD, Gene ID: 5226, Accession: NP_002622 |
Catalog # | MBS203633 |
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Order / More Info | PGD, 1-483aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
Product Specific References | Le TD., et al. (2010) Proc Natl Acad Sci u S A. 107 (7):3198-203. ; Tagen M., et al. (2009) J Immunol. 183 (10):6313-9.; |
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