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Product Name | NRG4, 1-61aa, Human, His tag, E Coli |
Description | MW: 9.1kDa (84aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. NRG4 belongs to the neuregulin family and contains 1 EGF-like domain. The protein is low affinity ligand for the ERBB4 tyrosine kinase receptor. It concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. NRG4 does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Recombinant human NRG4 protein, fused to His-tag at N-terminus, was expressed i |
Size | 0.05 mg, 0.25 mg |
Concentration | 0.25 mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | [Pro-neuregulin-4 membrane-bound isoform; Pro-neuregulin-4; membrane-bound isoform; Neuregulin 4; HRG4] |
Gene, Accession, CAS # | NRG4, Gene ID: 145957, Accession: NP_612640 |
Catalog # | MBS205320 |
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Order / More Info | NRG4, 1-61aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
Product Specific References | Zody M.C., Garber M et al. (2006), Nature 440:671-675 |
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