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| Product Name | Recombinant Human Single-stranded DNA cytosine deaminase (AICDA) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 28.0kDa. Full Length: 1-198aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes by deaminating C to U during transcription of Ig-variable and Ig-switch region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Activation-induced cytidine deaminase (AID) (Cytidine aminohydrolase) |
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| Gene, Accession, CAS # | AICDA, UniProt: Q9GZX7 |
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| Catalog # | RPC26381 |
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| Order / More Info | Recombinant Human Single-stranded DNA cytosine deaminase (AICDA) from BIOMATIK |
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| Product Specific References | n/a |
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