| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | APC11 |
|---|
| Clone | OTI1F2 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 µl |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:4000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | APC11 Monoclonal Antibody (OTI1F2). Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions a |
|---|
| Immunogen | n/a |
|---|
| Other Names | HSPC214, APC11, Apc11p; APC11 anaphase promoting complex subunit 11 homolog; anaphase promoting complex subunit 11 (yeast APC11 homolog); anaphase-promoting complex subunit 11; cyclosome subunit 11; hepatocellular carcinoma-associated RING finger protein |
|---|
| Gene, Accession # | Entrez: 51529; Uniprot: Q9NYG5 |
|---|
| Catalog # | MA5-26262 |
|---|
| Price | |
|---|
| Order / More Info | APC11 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|