产品详情 |
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Antigenic Specificity | APC13 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC13 Polyclonal Antibody. Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of |
Immunogen | n/a |
Other Names | APC13, SWM1; anaphase-promoting complex subunit 13; cyclosome subunit 13 |
Gene, Accession # | Entrez: 25847; Uniprot: Q9BS18 |
Catalog # | PA5-61154 |
Price | |
Order / More Info | APC13 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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