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| Antigenic Specificity | APC5 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 400 µL |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 1:10-1:50, Western Blot: 1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | APC5 Polyclonal Antibody. This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream |
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| Immunogen | n/a |
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| Other Names | APC5, anaphase-promoting complex subunit 5, cyclosome subunit 5 |
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| Gene, Accession # | Entrez: 51433; Uniprot: Q9UJX4 |
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| Catalog # | PA5-24454 |
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| Price | |
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| Order / More Info | APC5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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