产品详情 |
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Antigenic Specificity | APC7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 10 µL |
Concentration | n/a |
Applications | Immunohistochemistry: 1:100-1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC7 Polyclonal Antibody. Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a |
Immunogen | n/a |
Other Names | APC7, anaphase-promoting complex subunit 7; cyclosome subunit 7 |
Gene, Accession # | Entrez: 51434, 56317; Uniprot: Q9UJX3, Q9WVM3 |
Catalog # | IHC-00706-T |
Price | |
Order / More Info | APC7 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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