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| Product Name | Oleic Acid Alkyne |
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| Description | Purity >95%. Oleic acid is a monounsaturated fatty acid and is one of the major components of membrane phospholipids. Oleic acid contributes about 17% of the total fatty acids esterified to phosphatidylcholine, the major phospholipid class in porcine platelets. Oleic acid inhibits collagen-stimulated platelet aggregation by approximately 90% when used at a concentration of 10 µg/ml. fMLF-induced neutrophil aggregation and degranulation is inhibited by 55% and 68%, respectively, using 5 µM oleic acid. This inhibition is comparable to that observed using arachidonic acid under the same conditions. Oleic acid, whether applied extracellularly (EC50 = ~60 µM) to human platelets or released from membrane phospholipids, causes an increase in intracellular calcium levels. Oleic acid alkyne is a form of oleic acid with an ?-terminal alkyne. The terminal alkyne group can be used in click chemistry linking reactions, to tag oleic acid with fluorescent or biotinylated labels for analysis of its metabolism and biological activity. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (9Z)-9-octadecen-17-ynoic acid, Oleic Acid Alkyne |
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| Gene, Accession, CAS # | CAS: 151333-45-8 |
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| Catalog # | LS-H9159 |
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| Price | |
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| Order / More Info | Oleic Acid Alkyne from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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