| 产品详情 |
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| Antigenic Specificity | SIX3/SIX6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:1000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SIX3/SIX6 Polyclonal Antibody. The SIX proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Two of these family members Six3 and Six6 (also designated Optx2 and Six9) are required for the specification and proliferation of the eye field in vertebrates, and, therefore, are the vertebrate homologues most closely related to the Drosophila sine oculis protein, which has an essential role in controlling compound eye development. Six3 and Six6 expression largely overlap during development of specific tissues, such as retina, hypothalamus, and pituitary. Deletion of Six3 may be associated with HPE2 disorder, a common, severe malformation of the brain that results from incomplete cleava |
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| Immunogen | n/a |
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| Other Names | Homeobox protein SIX3; Sine oculis homeobox homolog 3; SIX3; HPE2; Homeobox protein SIX6; Homeodomain protein OPTX2; Optic homeobox 2; SIX6; OPTX2; SIX9 |
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| Gene, Accession # | Entrez: 20473, 20476, 314221, 4990, 6496, 78974; Uniprot: O95343, O95475, Q62233, Q9QZ28 |
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| Catalog # | PA5-75220 |
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| Price | |
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| Order / More Info | SIX3/SIX6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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