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Product Name | PPP3R1, 1-170aa, Human, His tag, E Coli |
Description | MW: 21.5 kDa (190aa), confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. PPP3R1, also known as Calcineurin subunit B type 1, is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase that plays an essential role in the T cell activation pathway. Calcineurin is composed of two subunits; calcineurin A (CnA) and calcineurin B (CnB). Dephosphorylation of the nuclear factor of activated T-cells (NF-AT) by Calcineurin is essential for NF-AT activation, nuclear translocation, and early g |
Size | 0.1 mg, 0.5 mg |
Concentration | 1 mg/ml (determined by Bradford assay) |
Applications | SDS-PAGE |
Other Names | [Protein phosphatase 3 regulatory subunit B alpha; Calcineurin subunit B type 1; CALNB1; CNB; CNB1] |
Gene, Accession, CAS # | PPP3R1, Gene ID: 5534, Accession: NP_000936 |
Catalog # | MBS203926 |
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Order / More Info | PPP3R1, 1-170aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
Product Specific References | Wang MG., et al. (1996) Cytogenet Cell Genet. 72 (2-3):236-41. |
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