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Antigenic Specificity | PI3 Kinase p110 beta Ser1070 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, IHC-P, IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PI3 Kinase p110 beta(Ser1070) Antibody. • Target Background: Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon |
Immunogen | KLH conjugated synthetic phosphopeptide derived from human PI3 Kinase p110 beta around the phosphorylation site of Ser1070. Immunogen Range: 1020-1070/1070 |
Other Names | Phosphorylated, phospho-Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; PI3-kinase subunit beta; PI3K-beta; PI3Kbeta; PtdIns-3-kinase subunit beta; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; PtdIns-3-kinase subunit p110-beta; p110beta; PIK3CB; PIK3C1 |
Gene, Accession # | Gene ID: 5291, SwissProt: P42338 |
Catalog # | bs-6417R |
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Order / More Info | PI3 Kinase p110 beta Ser1070 Antibody from BIOSS ANTIBODIES |
Product Specific References | Qiao, Jingwen, et al. (2017) Neurosci Lett. PubMed: 28366776 // Li, Zhao, et al. (2017) Biomed Res. // Liu, et al. (2018) Angiogenesis. 21:237-249. PubMed: 29299781 |
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