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Antigenic Specificity | Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (aa 1-16), (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | KCNIP3, also known as Calsenilin, is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system, thyroid gland, testis, thymus, and immune cells. This gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, which belong to the neuronal calcium sensor family of proteins. KCNIP3 is mapped to 2q11.1. The encoded protein functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes. KCNIP3 has been shown to interact with PSEN1 and PSEN2. |
Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human CSEN(1-16aa MQPAKEVTKASDGSLL). |
Other Names | KCNIP3|CSEN|DREAM|KCHIP3|4933407H12Rik|AI413860|Csen|KChIP3|R74849|Dream|rKChIP3|csen|im:7145308|kcnip3|zgc:73306 |
Gene, Accession # | Gene ID: 30818 |
Catalog # | ABIN1889220 |
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Order / More Info | Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (aa 1-16), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 21059893 |
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