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| Antigenic Specificity | XRN1 |
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| Clone | 7C8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 κ |
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| Format | Protein G purified |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | XRN1 (7C8) Monoclonal Antibody. • Target Background: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS). |
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| Immunogen | This XRN1 antibody is generated from a mouse immunized with arecombinant protein between1455-1706 amino acids from human XRN1. |
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| Other Names | SEP1; 5'-3' exoribonuclease 1; Strand-exchange protein 1 homolog; XRN1 |
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| Gene, Accession # | Gene ID: 54464, SwissProt: Q8IZH2 |
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| Catalog # | bsm-51355M |
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| Price | |
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| Order / More Info | XRN1 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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