| 产品详情 |
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| Product Name | IQ-1 |
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| Description | Purity >98%. IQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that maintains long-term mouse embryonic stem cell (ESC) pluripotency. When used at 4 µg/ml with Wnt3a, it allows ESCs to form embryoid bodies that continue to express markers of pluripotency, including Alpha-fetoprotein and Beta-III tubulin. IQ-1 blocks the interaction of the protein Naked cuticle with a subunit of the protein phosphatase PP2A, altering signaling through Wnt/Beta-catenin and maintaining the expression of stem cell markers Oct4, Nanog, and Rex1 in ESCs. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide |
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| Gene, Accession, CAS # | CAS: 331001-62-8 |
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| Catalog # | LS-H8233 |
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| Order / More Info | IQ-1 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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