| 产品详情 |
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| Product Name | ARL2, Recombinant, Human, aa19-184, GST-Tag (ADP-ribosylation Factor-like Protein 2) |
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| Description | Purity ~90% (SDS-PAGE). Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassbly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca2+-dependent release of acetylcholine. Required for normal progress through the cell cycle. Source: Recombinant protein corresponding to aa19-184 from human ARL2, fused to GST-Tag at N-terminal |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P36404 |
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| Catalog # | 372332 |
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| Order / More Info | ARL2, Recombinant, Human, aa19-184, GST-Tag (ADP-ribosylation Factor-like Protein 2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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