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| Product Name | MHC Class I Polypeptide-Related Sequence A (MICA) (C-Term), (AA 23-308) protein (Fc Tag) |
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| Description | Recombinant Human MHC Class I Polypeptide-Related Sequence A/MICA is produced with our HEK293 expression system. The target protein is expressed with sequence (Ala23-Glu308) of Human MICA fused with a FC tag at the C-terminus. MHC class I polypeptide-related sequence A, also known as MIC-A, PERB11.1 and MICA, is a single-pass type I membrane protein which belongs to the MHC class I family of MIC subfamily. MICA contains one Ig-like C1-type domain and is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with β-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by NK cells, NKT cells, and most of the subtypes of T cells. MICA is the ligand for NK cell activating receptor KLRK1/NKG2D. MICA seems to have no role in antigen presentation. MICA leads to cell lysis by binding to KLRK1. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Ica|mICA|FLJ60820|PERB11.1|MGC111087|MIC-A |
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| Gene, Accession, CAS # | Gene ID: 100507436 |
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| Catalog # | ABIN1692274 |
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| Order / More Info | MHC Class I Polypeptide-Related Sequence A (MICA) (C-Term), (AA 23-308) protein (Fc Tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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