| 产品详情 |
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| Product Name | 3-PT-PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt) |
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| Description | Purity >98%. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns(4,5)-P2 can be phosphorylated by phosphoinositide (PI)-3-kinase to make PtdIns(3,4,5)-P3 which initiates an intricate signaling cascade that has been implicated in cancer. 3-PT-PtdIns(3,4,5)-P3 is an analog of PtdIns-(3,4,5)-P3 that is resistant to hydrolysis by PTEN. It has a 5-fold reduced affinity for the specific PtdIns(3,4,5)-P3 -binding protein GRP1 and increases sodium transport in A6 cell monolayers. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(1,2-dioctanoylphosphatidyl)inositol-3-phosphorothioate-4,5-diphosphate, tetrasodium salt, 3-Phosphorothioate-Phosphatidylinositol-4,5-diphosphate C-8 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H6080 |
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| Price | |
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| Order / More Info | 3-PT-PtdIns-(3,4,5)-P3 (1,2-dioctanoyl) (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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