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| Product Name | 6-Formylpterin |
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| Description | Purity >98%. Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2 O2 ), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photolytic breakdown of folic acid. It binds to one of two active sites on XO nearly quantitatively and irreversibly and prevents the metabolism of other substrates at the second site, resulting in hetero-substrate inhibition at nanomolar concentrations. However, 6-formylpterin itself is converted by XO to 6-carboxylpterin and H2 O2 and the turnover rate of this reaction can actually be accelerated by prior binding of a hetero-substrate to XO. In this way, 6-formylpterin acts as an intracellular generator of H2 O2 in cells expressing XO, altering cellular function. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-amino-3,4-dihydro-4-oxo-6-pteridinecarboxaldehyde, 2-Amino-6-formylpteridin-4-one, 6-FP, Pterin-6-aldehyde |
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| Gene, Accession, CAS # | CAS: 712-30-1 |
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| Catalog # | LS-H6254 |
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| Order / More Info | 6-Formylpterin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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