产品详情 |
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Antigenic Specificity | TMEM66 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TMEM66 Polyclonal Antibody. Saraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions. |
Immunogen | n/a |
Other Names | FOAP-7, XTP3, HBV X-transactivated gene 3 protein, HBV XAg-transactivated protein 3, protein FOAP-7 |
Gene, Accession # | Entrez: 51669; Uniprot: Q96BY9 |
Catalog # | PA5-31588 |
Price | |
Order / More Info | TMEM66 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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