| 产品详情 |
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| Antigenic Specificity | TMEM88 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 20 µg/mL, Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TMEM88 Polyclonal Antibody. Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner. |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 497936, 67020, 92162; Uniprot: Q6PEY1, Q9D0N8 |
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| Catalog # | PA5-21164 |
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| Price | |
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| Order / More Info | TMEM88 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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