| 产品详情 |
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| Product Name | Orlistat |
| Description | Purity >98% by HPLC. Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolemic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (FASN). Anti-proliferative. Causes cell cycle arrest at G1 phase. Apoptosis inducer through caspase-3 activation. Sn-1-selective-diacylglycerol lipases alpha (DAGLalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (DAGL), which is responsible for the conversion of DAG to 2-AG. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to TRAIL in cancer cells by ROS-mediated pathways. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Alli, Ro-18-0647, Tetrahydrolipstatin, Xenical |
| Gene, Accession, CAS # | CAS: 96829-58-2 |
| Catalog # | LS-H348 |
| Price | |
| Order / More Info | Orlistat from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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