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| Product Name | 4-Quinolone-3-Carboxamide CB2 Ligand |
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| Description | Purity >98%. Cannabinoids (CBs) and their synthetic analogs produce biochemical and pharmacological effects by interacting with the central CB1 and peripheral CB2 receptors. The CB2 receptor has emerged as a pharmacotherapeutic target for treating osteoporosis, as well as for eliciting antinociceptive effects in various models of pain. 4-Quinolone-3-carboxamide CB2 ligand is a selective, high-affinity ligand of the CB2 receptor, displaying a Ki value of 0.6 nM (Ki >10,000 nM for CB1 ) in vitro . At a dose of 6 mg/kg, 4-quinolone-3-carboxamide CB2 ligand exhibits antinociceptive activity in a formalin test of nocifensive response in mice. This analgesic affect is not significantly reversed by the CB2 antagonist AM630 , which suggests 4-quinolone-3-carboxamide CB2 ligand may behave as an inverse agonist. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1,4-dihydro-8-methoxy-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-3-quinolinecarboxamide, 4Q3C CB2 Ligand |
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| Gene, Accession, CAS # | CAS: 1314230-69-7 |
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| Catalog # | LS-H6155 |
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| Order / More Info | 4-Quinolone-3-Carboxamide CB2 Ligand from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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