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| Product Name | Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) (Active) protein (His tag) |
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| Description | AKR1C3 is part of the aldo/keto reductase superfamily, which has at least 40 identified proteins. AKR1C3 catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. AKR1C3 displays overlapping but distinct substrate specificity. AKR1C3 catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. AKR1C3 is involved in the pathogenesis of allergic diseases such as asthma. AKR1C3 controls cell growth and/or differentiation. AKR1C3, having ability to convert androstenedione to testosterone, itakes part in adrenal testosterone production. AKR1C3 expression is affected by metabolic disease, and its levels are considerably reduced in response to diet-induced weight loss and correlate with leptin levels Synonyms: DD3, DDX, HAKRB, HAKRe, HA1753, HSD17B5, hluPGFS, KIAA0119, AKR1C3, Aldo-keto reductase family 1 member C3, 3-alpha-HSD type 2, 17-beta-HSD 5, PGFS, DD-3 |
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| Size | 20 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AKR1C3|PGFS|MGC134333|DD3|DDX|HA1753|HAKRB|HAKRe|HSD17B5|hluPGFS|Akr1c18 |
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| Gene, Accession, CAS # | Gene ID: 8644 |
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| Catalog # | ABIN805678 |
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| Order / More Info | Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) (Active) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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